CATH Domain: 1czqA00 XML data for domain: 1czqA00

Molscript image for 1czqA00
1czqA00
PDB coordinates for domain 1czqA00

PDB 1czq, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.3
1.20.5.170.3.1
1.20.5.170.3.1.1
1.20.5.170.3.1.1.1
1.20.5.170.3.1.1.1.1

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Segment boundaries for domain 1czqA00

Chopping figure for domain 1czqA00
DomainStart PDB ResidueStop PDB Residue
1czqA00 1 45

Structural Neighbourhood (103 entries)

There are 103 matching structural neighberhood comparisons for CATH ID 1.20.5.170.3.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 103 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1jekA00 92.36 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 15 80 0.44 0.55
1r8eA03 91.89 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 15 84 0.42 0.50
1junA00 90.45 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 11 84 0.80 0.95
1hf9A00 90.34 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 12 91 1.14 1.25
1ik7A00 89.84 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 2 86 1.45 1.68
1n2dC00 89.74 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 8 87 1.67 1.91
1jnmA00 89.68 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 8 80 0.88 1.10
3e7kA00 89.61 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 4 77 0.79 1.02
1nkzB00 88.83 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 9 84 3.17 3.75
1ci6B00 88.73 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 4 91 1.75 1.91
1piqA00 88.59 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 83 68 0.40 0.58
1lghB00 88.23 Phaeospirillum molischianumLight-harvesting protein B-800/850 beta 1 chain 1.20.5.250 43 4 82 2.92 3.55
2basA02 88.20 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 11 93 2.65 2.83
1g2cB00 88.13 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 2 88 3.45 3.88
1e5wA04 88.09 Leukocyte migrationReceptor bindingCytoskeletonMembrane to membrane dockingNucleolus 1.20.5.450 55 6 81 1.37 1.67
1tiiC00 87.74 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 11 80 1.68 2.10
1pfiA00 87.45 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 4 89 2.05 2.30
1ifpA00 87.15 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 11 75 1.10 1.46
2p7jB01 86.93 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 12 86 2.64 3.05
1ybkA00 86.84 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 8 78 2.35 2.98
2ifoA00 86.72 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 0 82 1.50 1.82
1kv4A00 86.41 Moricin-1Bombyx mori 1.20.5.750 42 9 77 1.60 2.06
3effK02 86.26 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 4 77 1.93 2.48
2zxeB01 86.18 1.20.5.170 35 5 77 2.75 3.54
3efgA00 85.57 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 11 87 2.92 3.33
2o1kA00 85.49 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 7 77 1.74 2.24
1omiA02 85.38 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 11 60 0.49 0.82
1uixA00 85.33 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 17 66 1.01 1.53
1ic2B00 85.25 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 13 58 0.51 0.87
1nwqA00 84.99 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 17 75 2.15 2.87
1s5lX00 84.87 Photosystem II reaction center X proteinThermosynechococcus elongatus BP-1 1.20.5.510 40 5 71 2.01 2.83
2k1aA00 84.69 Integrin alpha 2BIdentical protein bindingPathways in cancerHematopoietic cell lineageDilated cardiomyopathy 1.20.5.930 42 7 84 3.38 4.00
3b8eB00 84.63 Sodium/potassium-transporting ATPase subunit beta-1Sus scrofa 1.20.5.170 46 0 84 2.72 3.21
1pl5A00 84.44 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 6 60 0.96 1.60
1gmjD00 84.30 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 6 67 1.61 2.37
1a2xB00 83.84 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 19 60 0.84 1.40
1wt6B00 83.80 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 6 67 1.67 2.49
1favA00 83.61 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 44 57 0.54 0.94
1l2pA00 83.60 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 8 52 0.44 0.84
2pjuD03 83.54 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 1.20.5.170 41 4 64 1.94 3.01
1jmmA01 83.53 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 15 64 1.22 1.89
1m7lA00 83.32 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 2 80 2.74 3.42
1avyA00 83.00 Enterobacteria phage T4Fibritin 1.20.5.320 68 11 64 3.13 4.84
1ltsC00 82.91 Heat-labile enterotoxin A chainEscherichia coli 1.20.5.240 41 2 55 0.55 0.99
1jcdB00 82.91 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 6 61 1.53 2.49
2hr3A01 82.74 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 6 64 1.85 2.87
2rklB00 82.66 Multivesicular bodyVacuolar protein sorting-associated protein VTA1Membrane fractionProtein bindingEndocytosis 1.20.5.420 50 4 64 1.75 2.73
1u57A00 82.12 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 4 75 3.45 4.60
1svfC00 82.02 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 0 62 2.24 3.56
2p2uA01 81.96 Desulfovibrio vulgaris str. HildenboroughHost-nuclease inhibitor protein Gam, putative 1.20.5.170 69 20 63 1.15 1.80
1xrdA01 81.77 Light-harvesting complex 1 alpha chainRhodospirillum rubrumLight-harvesting protein B-870 alpha chain 1.20.5.890 43 6 75 3.35 4.43
1owaA01 81.70 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 0 71 2.45 3.45
1a02F00 81.65 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 2 64 1.85 2.88
2qjyC01 81.26 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 9 53 0.65 1.22
1jocA01 80.95 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 6 53 0.69 1.29
1nknA00 80.66 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 8 60 1.76 2.89
1gu4A00 80.64 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 13 58 2.75 4.70
1dh3A00 80.54 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 8 65 1.84 2.81
3fx7A00 80.36 Helicobacter pyloriPutative uncharacterized protein 1.10.287.850 83 6 51 1.27 2.45
1s3jB01 79.81 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 3 66 2.61 3.92
3gwoA00 79.64 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 6 67 3.17 4.67
2wpqA00 79.45 Salmonella enterica subsp. enterica serovar TyphimuriumPutative inner membrane protein 1.20.5.980 99 62 44 0.48 1.08
2b9bA04 79.01 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 6 46 2.22 4.75
2oarE02 78.98 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 4 48 1.47 3.01
1mqsB00 78.76 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 3 57 1.48 2.56
1hj0A00 78.22 Bos taurusThymosin beta-10 1.20.5.520 41 4 48 0.94 1.92
1mg1A03 78.13 Bacterial chemotaxisABC transportersMaltose/maltodextrin transport system substrate-binding proteinEscherichia coli O157:H7Maltose-binding periplasmic protein 1.10.287.210 84 4 46 1.16 2.50
2k37A00 77.84 Bacteriochlorophyll c-binding proteinChlorobaculum tepidumChlorosome envelope protein A 1.20.5.950 59 2 57 2.01 3.49
1ozhA03 77.63 Acetolactate synthase, catabolicKlebsiella pneumoniae 1.20.5.740 24 16 53 2.00 3.75
1ytzT00 77.47 Troponin T, fast skeletal muscle isoformsGallus gallus 1.20.5.350 90 17 50 1.18 2.36
2p10B02 76.70 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 11 44 0.69 1.55
1fd9A02 76.48 FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]Outer membrane protein MIPLegionella pneumophila subsp. pneumophila str. Philadelphia 1 1.10.287.460 98 4 45 1.25 2.72
1avyB00 76.47 Enterobacteria phage T4Fibritin 1.20.5.320 54 4 51 2.26 4.36
2dw4A03 76.26 Lysine-specific histone demethylase 1AHistone demethylase activityNucleusTranscription repressor activityHomo sapiens 1.10.287.80 101 4 41 1.23 2.96
1fdoA05 76.07 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 3 48 1.26 2.58
1d7mA00 76.05 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 6 44 1.40 3.14
1gk4C00 76.02 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 4 42 2.05 4.78
1wdcA00 75.91 Myosin heavy chain, striated muscleArgopecten irradians 4.10.270.10 64 8 42 1.03 2.44
3c8vA04 75.72 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 10 42 0.71 1.68
2r44A01 75.65 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 0 57 2.49 4.31
1envA00 75.52 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 115 8 39 0.90 2.30
2o01J01 75.41 Photosystem I reaction center subunit IXSpinacia oleracea 1.20.5.510 25 8 55 2.60 4.68
1kqfB03 75.27 Two-component systemMetabolic pathwaysGlyoxylate and dicarboxylate metabolismMethane metabolismFormate dehydrogenase activity 1.20.5.480 44 4 53 2.38 4.46
3ii6A02 75.24 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 4 39 0.72 1.82
1vf5C03 74.48 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 3 37 0.38 1.01
1be3K00 73.57 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 13 40 0.83 2.08
2zvoB00 73.28 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 88 4 39 1.40 3.52
2qiwA02 72.77 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 16 40 0.85 2.12
1h8bB00 72.49 TitinOryctolagus cuniculus 1.20.5.510 23 4 35 0.33 0.93
2rh0A02 72.19 Mus musculusNudC domain-containing protein 2 1.20.5.740 29 3 42 1.83 4.33
1fxkC00 72.09 Methanothermobacter thermautotrophicus str. Delta HPrefoldin subunit alphaPrefoldin alpha subunit 1.10.287.370 133 17 33 1.51 4.46
1l8dA00 72.06 Exonuclease SbcCPyrococcus furiosusDNA double-strand break repair rad50 ATPase 1.10.287.510 103 6 35 1.57 4.37
1csbA01 71.17 Regulation of apoptosisLysosomeHomo sapiensCathepsin B [EC:3.4.22.1]Cathepsin B 1.20.5.170 42 0 42 1.57 3.72
3kpeA00 71.05 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 6 31 0.35 1.10
1mslA02 70.59 1.20.5.220 18 11 40 1.12 2.80
2b5uA02 70.04 Colicin-E3Escherichia coli 1.10.287.620 161 6 27 0.61 2.18
1d66B02 68.02 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 6 33 0.77 2.31
1ik9B02 67.85 DNA ligation involved in DNA repairResponse to X-rayDNA-dependent protein kinase-DNA ligase 4 complexProtein C-terminus bindingDouble-strand break repair via nonhomologous end joining 1.20.5.370 83 2 25 0.42 1.66
2oarA02 67.68 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 11 28 0.27 0.93
1io1A01 67.14 FlagellinTwo-component systemSalmonella enterica subsp. enterica serovar TyphimuriumFlagellar assemblyFlagellin 1.20.1330.10 169 2 26 1.03 3.87
1mkmA02 65.23 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 14 31 0.67 2.15
3fwnA03 64.11 Glutathione metabolismMetabolic pathwaysPentose phosphate pathwayProtein bindingEscherichia coli K-12 1.20.5.320 34 5 31 1.27 4.08
1hciA01 63.64 Alpha-actinin-2NucleolusZASP bindingFATZ 1 bindingMicrospike assembly 1.20.58.60 126 8 25 1.14 4.49
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Displaying entries 1 to 103 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1czqA00
RMKQIEDKIEEIESKQKKIENEIARIKKLLQLTVWGIKQLQARIL
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1czqA00
XRMKQIEDKIEEIESKQKKIENEIARIKKLLQLTVWGIKQLQARIL
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"