CATH Domain: 1btnA00 XML data for domain: 1btnA00

Molscript image for 1btnA00
1btnA00
PDB coordinates for domain 1btnA00

PDB 1btn, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.29 PH-domain like
2.30.29.30 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) Gene3D
2.30.29.30.18
2.30.29.30.18.1
2.30.29.30.18.1.1
2.30.29.30.18.1.1.1
2.30.29.30.18.1.1.1.1

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Segment boundaries for domain 1btnA00

Chopping figure for domain 1btnA00
DomainStart PDB ResidueStop PDB Residue
1btnA00 1 106

Structural Neighbourhood (20 entries)

There are 20 matching structural neighberhood comparisons for CATH ID 2.30.29.30.18.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 20 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3cxbB00 86.50 Kinesin bindingPleckstrin homology domain-containing family M member 2Golgi organizationHomo sapiens 2.30.29.30 102 23 89 4.07 4.54
2dhjA00 86.16 Rho GTPase-activating protein 21Homo sapiens 2.30.29.30 125 31 82 2.44 2.96
1qqgA01 85.63 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 103 16 84 1.83 2.16
2dn6A00 83.85 CytoplasmPlasma membraneSwitch-associated protein 70Homo sapiens 2.30.29.30 115 17 79 1.96 2.48
1v89A00 83.85 Homo sapiensRho GTPase-activating protein 25 2.30.29.30 118 17 77 2.52 3.23
1omwA05 83.76 MembraneNegative regulation of the force of heart contraction by chemical signalG-protein coupled receptor kinase activityChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 2.30.29.30 101 13 78 2.18 2.78
1qqgA02 83.35 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 104 11 83 2.85 3.39
1dynA00 83.17 GTPase activityReceptor-mediated endocytosisHomo sapiensDynamin-1Protein binding 2.30.29.30 113 14 83 2.77 3.33
1plsA00 82.86 Soluble fractionInhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathwayHemopoietic progenitor cell differentiationActin cytoskeleton reorganizationRegulation of cell diameter 2.30.29.30 113 23 81 2.31 2.84
2rgnB02 81.85 Homo sapiensGuanine nucleotide exchange factor GEFT 2.30.29.30 123 10 69 2.17 3.10
2he7A03 81.60 Tight junctionErythrocyte membrane protein band 4.1Homo sapiensBand 4.1-like protein 3Cell-cell junction 2.30.29.30 95 4 73 2.13 2.89
1kz7C02 81.48 Mus musculusGuanine nucleotide exchange factor DBSRho guanyl-nucleotide exchange factor activityRho protein signal transductionLamellipodium 2.30.29.30 134 12 67 2.58 3.84
2coaA01 80.93 Homo sapiensSerine/threonine-protein kinase D2 2.30.29.30 118 15 77 2.36 3.06
1v88A00 80.79 Oxysterol-binding protein-related protein 8Homo sapiens 2.30.29.30 130 17 67 2.22 3.28
1ef1A03 80.72 Receptor bindingLeukocyte migrationCytoskeletonMembrane to membrane dockingNucleolus 2.30.29.30 95 7 76 2.41 3.15
1p5tA00 79.59 Mus musculusRas protein signal transductionDocking protein 1Transmembrane receptor protein tyrosine kinase signaling pathwayTransmembrane receptor protein tyrosine kinase signaling protein activity 2.30.29.30 105 8 83 3.73 4.44
1mixA02 78.92 Talin-1Focal adhesionFocal adhesionGallus gallusTalin 2.30.29.30 93 12 77 3.17 4.10
1rrpB00 78.35 E3 SUMO-protein ligase RanBP2Ran GTPase bindingNuclear poreProtein import into nucleusHomo sapiens 2.30.29.30 134 5 69 3.39 4.88
1btkA00 77.29 Induction of apoptosis by extracellular signalsPhosphatidylinositol-3,4,5-trisphosphate bindingIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.29.30 160 10 60 2.93 4.88
1pfjA00 77.05 Positive regulation of transcription from RNA polymerase II promoterGeneral RNA polymerase II transcription factor activityGeneral transcription factor IIH subunit 1Nucleotide excision repairRegulation of cyclin-dependent protein kinase activity 2.30.29.30 108 9 77 3.52 4.53
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Displaying entries 1 to 20 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1btnA00
MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIPYHSEVPVSLKEAICEVALDYKKKKHVFKLRL
SDGNEYLFQAKDDEEMNTWIQAISSA
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1btnA00
MEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKSAASGIPYHSEVPVSLKEAICEVALDYKKKKHVFKLRL
SDGNEYLFQAKDDEEMNTWIQAISSA
BLAST against CATH

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Domain History Events (4)

Update comment by auto on 16 Oct 2007 19:44

Around September/October 2007, this domain was renamed from "1btn000" to "1btnA00" as part of the work to deal with the remediation of the PDB (see http://remediation.wwpdb.org). Please see ticket:207 or wiki:Remediation on the CATH Trac system for more details.

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"