CATH Domain: 1aqcA00 XML data for domain: 1aqcA00

Molscript image for 1aqcA00
1aqcA00
PDB coordinates for domain 1aqcA00

PDB 1aqc, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.29 PH-domain like
2.30.29.30 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) Gene3D
2.30.29.30.20
2.30.29.30.20.1
2.30.29.30.20.1.2
2.30.29.30.20.1.2.1
2.30.29.30.20.1.2.1.1

Segment boundaries for domain 1aqcA00

Chopping figure for domain 1aqcA00
DomainStart PDB ResidueStop PDB Residue
1aqcA00 324 488

Structural Neighbourhood (16 entries)

There are 16 matching structural neighberhood comparisons for CATH ID 2.30.29.30.20.1.2.1.1 (SIMAX score < 5)

Displaying entries 1 to 16 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1qqgA02 85.30 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 104 10 79 3.85 4.82
2he7A03 84.49 Tight junctionErythrocyte membrane protein band 4.1Homo sapiensBand 4.1-like protein 3Cell-cell junction 2.30.29.30 95 8 71 1.91 2.69
1ntvA00 83.72 Radial glia guided migration of Purkinje cellDisabled homolog 1Cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migrationNegative regulation of cell adhesionMus musculus 2.30.29.30 152 18 75 3.25 4.33
1mixA02 82.73 Talin-1Focal adhesionFocal adhesionGallus gallusTalin 2.30.29.30 93 13 72 3.16 4.34
1ef1A03 82.15 Receptor bindingLeukocyte migrationCytoskeletonMembrane to membrane dockingNucleolus 2.30.29.30 95 10 72 2.58 3.54
1xr0B01 81.94 Fibroblast growth factor receptor substrate 2Membrane fractionIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase adaptor activityNeurotrophin signaling pathway 2.30.29.30 91 5 75 3.00 3.98
2rgnB02 81.28 Homo sapiensGuanine nucleotide exchange factor GEFT 2.30.29.30 123 8 77 2.92 3.78
3cxbB00 80.82 Kinesin bindingPleckstrin homology domain-containing family M member 2Golgi organizationHomo sapiens 2.30.29.30 102 8 73 2.74 3.72
1omwA05 80.78 MembraneNegative regulation of the force of heart contraction by chemical signalG-protein coupled receptor kinase activityChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 2.30.29.30 101 8 74 3.07 4.12
1kz7C02 80.40 Mus musculusGuanine nucleotide exchange factor DBSRho guanyl-nucleotide exchange factor activityRho protein signal transductionLamellipodium 2.30.29.30 134 4 74 3.69 4.94
1qqgA01 80.28 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 103 7 66 2.58 3.87
1ddmA00 79.77 Notch signaling pathwaySensory organ precursor cell fate determinationSensory organ precursor cell divisionProtein localizationDrosophila melanogaster 2.30.29.30 135 17 75 2.60 3.44
1t77A01 79.71 Lipopolysaccharide-responsive and beige-like anchor proteinHomo sapiensProtein binding 2.30.29.40 105 4 65 3.15 4.79
1plsA00 77.68 Soluble fractionInhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathwayHemopoietic progenitor cell differentiationActin cytoskeleton reorganizationRegulation of cell diameter 2.30.29.30 113 7 82 4.05 4.91
1dbhA02 77.64 Jak-STAT signaling pathwayPathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancer 2.30.29.30 124 4 62 2.82 4.54
1v89A00 77.58 Homo sapiensRho GTPase-activating protein 25 2.30.29.30 118 4 73 3.32 4.50
Displaying entries 1 to 16 (page 1 of 1)


Domain ATOM Sequence

>pdb|1aqcA00
EDLIDGIIFAANYLGSTQLLSDKTPSKNVRQAQEAVSRIKAQKLTEVDLFILTQRIKVLNADTQETDHPLRTISYIADIG
NIVVLARRRYKICHVFESEDAQLIAQSIGQAFSVAYQEFLR    

Domain COMBS Sequence

>pdb|1aqcA00
XEDLIDGIIFAANYLGSTQLLSDKTPSKNVRXXQAQEAVSRIKXAQKLAKSRKKAPEGESQPXTEVDLFILTQRIKVLNA
DTQETXXDHPLRTISYIADIGNIVVLXARRRIPRSNSQENVEASHPSQDGKRQYKXICHVFESEDAQLIAQSIGQAFSVA
YQEFLRANGINP    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"