CATH Domain: 1a7sA01 XML data for domain: 1a7sA01

Molscript image for 1a7sA01
1a7sA01
PDB coordinates for domain 1a7sA01

PDB 1a7s, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.5
2.40.10.10.5.1
2.40.10.10.5.1.1
2.40.10.10.5.1.1.1
2.40.10.10.5.1.1.1.1

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Segment boundaries for domain 1a7sA01

Chopping figure for domain 1a7sA01
DomainStart PDB ResidueStop PDB Residue
1a7sA01 1 12
1a7sA01 108 207
1a7sA02 13 107
1a7sA02 208 221

Structural Neighbourhood (33 entries)

There are 33 matching structural neighberhood comparisons for CATH ID 2.40.10.10.5.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 33 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1eq9A01 90.70 Chymotrypsin-1Solenopsis invicta 2.40.10.10 117 34 93 1.55 1.66
1eaxA01 89.82 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 126 29 88 1.53 1.74
1gvkB01 89.39 Sus scrofaChymotrypsin-like elastase family member 1Protein binding 2.40.10.10 128 31 86 1.32 1.52
1k2i101 89.22 Bos taurusChymotrypsinogen A 2.40.10.10 118 26 88 1.41 1.58
1si5H01 88.95 Pathways in cancerHepatocyte growth factorEpithelial to mesenchymal transitionRenal cell carcinomaCytokine-cytokine receptor interaction 2.40.10.10 119 31 91 2.27 2.48
1bioA01 88.89 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 122 36 90 1.90 2.11
2o8tA01 88.87 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorSignal transductionProteolysis 2.40.10.10 128 26 86 1.43 1.65
2asuB01 88.58 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 122 32 87 2.30 2.62
1elvA02 87.79 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 126 25 85 1.97 2.30
2bvrH01 87.51 FibrinolysisSerine-type endopeptidase activityProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 132 30 83 1.85 2.22
2hlcA02 87.28 CollagenaseHypoderma lineatum 2.40.10.10 126 27 84 2.36 2.78
3gylB01 87.00 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 133 29 82 1.86 2.25
1nn6A01 86.78 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 114 29 93 2.71 2.89
1gvzA01 86.62 Equus caballusKallikrein-1E2 2.40.10.10 121 26 90 2.40 2.64
1q3xA02 86.52 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 137 29 81 2.18 2.69
2o8lA01 83.33 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 115 8 79 2.34 2.96
1y8tB02 83.13 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 111 14 77 2.53 3.26
1p3cA01 82.58 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 102 11 86 3.38 3.90
2qf3B02 81.89 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 103 16 75 2.47 3.29
1yphE00 81.63 Bos taurusChymotrypsinogen A 2.40.10.10 97 17 63 1.59 2.51
1lcyA02 81.47 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Endoplasmic reticulum membraneParkinson's diseaseNucleus 2.40.10.10 84 22 74 3.26 4.40
2qa9E02 81.43 Streptomyces griseusStreptogrisin-B 2.40.10.10 94 21 73 2.88 3.93
2j92A02 79.92 Foot-and-mouth disease virus (strain A10-61)Genome polyprotein 2.40.10.10 109 9 74 2.72 3.67
1arbA01 79.90 Achromobacter lyticusProtease 1 2.40.10.10 122 11 83 3.42 4.09
2o8mA02 78.91 Genome polyproteinHepatitis C virus subtype 1a 2.40.10.10 87 13 67 3.18 4.69
2halA02 78.76 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 103 6 72 2.98 4.12
1dleB02 77.85 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 142 16 61 2.49 4.02
1befA02 75.90 2.40.10.10 85 11 66 3.22 4.87
2h5cA01 75.80 Lysobacter enzymogenesAlpha-lytic protease 2.40.10.10 85 7 58 2.71 4.67
1svpA02 75.78 Sindbis virusStructural polyprotein 2.40.10.10 86 9 61 2.63 4.27
3fanA02 73.10 Porcine reproductive and respiratory syndrome virusNon-structural protein 2.40.10.10 69 13 55 2.25 4.06
2ck3D01 72.44 ATP catabolic processParkinson's diseaseOxidative phosphorylationAlzheimer's diseaseMetabolic pathways 2.40.10.170 73 6 47 2.33 4.92
2ey4C00 72.10 Pyrococcus furiosusSmall nucleolar rnp gar1-like proteinRNA-binding protein 2.40.10.230 73 6 51 2.32 4.48
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Displaying entries 1 to 33 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1a7sA01
IVGGRKARPRQFLPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDG
GTPLVCEGLAHGVASFSLGPCGRGPDFFTRVA
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1a7sA01
IVGGRKARPRQFLPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDG
GTPLVCEGLAHGVASFSLGPCGRGPDFFTRVA
BLAST against CATH

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Domain History Events (4)

Update comment by auto on 16 Oct 2007 19:44

Around September/October 2007, this domain was renamed from "1a7s001" to "1a7sA01" as part of the work to deal with the remediation of the PDB (see http://remediation.wwpdb.org). Please see ticket:207 or wiki:Remediation on the CATH Trac system for more details.

Set cath from cathlist by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:06

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"