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CATH Search: "proteolysis"

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Cathnodes (70)
Domains (2583)
Chains (1867)
Pdbs (930)

Start Browsing at the top of the CATH hierarchy		Browsing the CATH database You can start browsing through the CATH tree by starting at the least discriminatory classification level (Class) then working your way through to more discriminatory collections of domains ( Architecture, Topology, then Homologous Superfamily). Searching the CATH database by ID/Keywords You can search CATH with identifiers such as: PDB codes (e.g. 1cuk) PDB chains (e.g. 1cukA) CATH domain codes (e.g. 1cukA01) CATH classification codes (e.g. 1.10.10) You can also search for general keywords in CATH (e.g. Inhibitor). Searching the CATH database by FASTA sequence You can perform a quick BLAST search of the sequences in CATH by submitting a FASTA sequence.
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Query 'proteolysis' matched 5450 entries in the CATH database. The top hit for each type of entry given below. Click on the 'more' link or the tabs to see all the results.

Molscript image for 1r1hA02

Cathnode: Neutral endopeptidase , domain2

Related Keywords: Integral to plasma membranePlasma membraneHematopoietic cell lineageNeprilysinAlzheimer's diseaseProtein bindingProteolysisCell-cell signalingNeprilysinHomo sapiensRenin-angiotensin system

http://www.cathdb.info/cathnode/1.10.1380.10 - View all 70 matching cathnodes

Molscript image for 1yc6100

Domain: PDB code 1yc6, chain 1, domain 00

Related Keywords: WaterCoat proteinPolymerPolypeptide(L)Structural Transition, Proteolysis, BMV, AlMV, Symmetry, Assembly, Icosahedral virus60-mericVirus

http://www.cathdb.info/domain/1yc6100 - View all 2583 matching domains

Molscript image for 1gnv

Pdb: PDB code 1gnv

Related Keywords: WaterFibrinolysisSUBTILISIN BPN'PolymerPolypeptide(L)HYDROLASEProteolysisProtein bindingMonomericBacillus amyloliquefaciensBACILLUS AMYLOLIQUEFACIENSHYDROLASE, SERINE PROTEINASESubtilisin activitySubtilisin BPN' precursor

http://www.cathdb.info/pdb/1gnv - View all 930 matching pdbs

Molscript image for 1yc61

Chain: PDB code 1yc6, chain 1

Related Keywords: WaterCoat proteinPolymerPolypeptide(L)Structural Transition, Proteolysis, BMV, AlMV, Symmetry, Assembly, Icosahedral virus60-mericVirus

http://www.cathdb.info/chain/1yc61 - View all 1867 matching chains

Cathnodes (70)

ID	Title	Keywords
1.10.1380.10	Neutral endopeptidase , domain2	Neprilysin Hematopoietic cell lineage Alzheimer's disease Homo sapiens Cell-cell signaling
2.60.40.780	CATH superfamily 2.60.40.780	Negative regulation of cell proliferation Mitotic cell cycle Regulation of transcription Ubiquitin mediated proteolysis Proteolysis
1.10.750.10	Elongin C, Chain C domain 1	Negative regulation of cell proliferation Mitotic cell cycle Regulation of transcription Ubiquitin mediated proteolysis Proteolysis
3.10.20.260	Ubiquitin activating enzymes (Uba3). Chain: B, domain 3	Mitotic cell cycle Insoluble fraction S-m checkpoint Induction of apoptosis Ubiquitin mediated proteolysis
1.10.10.520	Ubiquitin activating enzymes (Uba3). Chain: B, domain 2	Mitotic cell cycle Insoluble fraction S-m checkpoint Induction of apoptosis Ubiquitin mediated proteolysis
3.90.370.10	Tissue inhibitor of metalloproteinase-1. Chain B, domain 1	Protease inhibitor Negative regulation of membrane protein ectodomain proteolysis Positive regulation of cell proliferation Blood cell Metalloproteinase inhibitor 2 precursor
1.20.1310.10	Cullin Repeats	Negative regulation of cell proliferation Cullin 1 Ubiquitin mediated proteolysis Cell cycle arrest Cullin-1
1.20.5.530	Single helix bin	Drosophila melanogaster Response to fungus Zygotic determination of dorsal/ventral axis Plasma membrane Toll signaling pathway
2.150.10.10	Alkaline Protease, subunit P, domain 1	Erwinia chrysanthemi Adhesin yada precursor Serralysin precursor Proteolysis Yersinia enterocolitica
3.30.70.850	CATH superfamily 3.30.70.850	Peptide biosynthetic process Proteolysis Extracellular space Proprotein convertase subtilisin/kexin type 1 Protein processing (proteolytic)
4.10.1030.10	Ring Box Chain A; domain 5	Negative regulation of cell proliferation Cullin 1 Ubiquitin mediated proteolysis Cell cycle arrest Cullin-1
4.10.180.30	CATH superfamily 4.10.180.30	Baculoviral iap repeat-containing 2/3/4 Apoptosis Ubiquitin mediated proteolysis Focal adhesion Anti-apoptosis
2.40.50.120	CATH superfamily 2.40.50.120	Calmodulin binding Metalloproteinase inhibitor 3 precursor Protease inhibitor Gallus gallus Negative regulation of membrane protein ectodomain proteolysis
3.10.290.20	Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3	Enzyme activator Ubiquitin mediated proteolysis Sumo-activating enzyme subunit 2 Assembly of protein complexes Ubiquitin-like 1-activating enzyme e1 b
1.10.3240.10	Ubiquitin-like 1 activating enzyme e1a, chain B, domain 2	Enzyme activator Ubiquitin mediated proteolysis Sumo-activating enzyme subunit 2 Assembly of protein complexes Ubiquitin-like 1-activating enzyme e1 b
2.40.128.80	CATH superfamily 2.40.128.80	Chloride ion binding Inflammatory response Immune response Aging Cytotoxic cell response (e.g. nk)
1.10.101.10	Muramoyl-pentapeptide Carboxypeptidase, domain 1	Extracellular matrix 72 kda type iv collagenase precursor Macrophage differentiation Extracellular matrix component Bladder cancer
1.10.720.30	CATH superfamily 1.10.720.30	Somatic / mitotic recombination E3 sumo-protein ligase pias1 Transcription corepressor activity Jak-stat signaling pathway Atp-dependent dna helicase 2 subunit 1
2.10.10.10	CATH superfamily 2.10.10.10	Extracellular matrix 72 kda type iv collagenase precursor Macrophage differentiation Extracellular matrix component Bos taurus
2.120.10.80	Kelch-like ech-associated protein 1	Kelch-like protein 12 Embryogenesis Transcriptional control Rna synthesis Transcription regulator activity

Domains (2583)

ID	Title	Keywords
1yc6100	PDB code 1yc6, chain 1, domain 00	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1yc6200	PDB code 1yc6, chain 2, domain 00	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1yc6300	PDB code 1yc6, chain 3, domain 00	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1yc6400	PDB code 1yc6, chain 4, domain 00	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1gnvA00	PDB code 1gnv, chain A, domain 00	Bacillus amyloliquefaciens Water Subtilisin activity Proteolysis Hydrolase, serine proteinase
1nddA00	PDB code 1ndd, chain A, domain 00	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1nddB00	PDB code 1ndd, chain B, domain 00	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1nddC00	PDB code 1ndd, chain C, domain 00	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1nddD00	PDB code 1ndd, chain D, domain 00	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1o0eA00	PDB code 1o0e, chain A, domain 00	Water Monomeric Plant cysteine protease, two domain, stable at ph 2-12, hydrolase Proteolysis Ervatamin-c
1o0eB00	PDB code 1o0e, chain B, domain 00	Water Monomeric Plant cysteine protease, two domain, stable at ph 2-12, hydrolase Proteolysis Ervatamin-c
1gnsA00	PDB code 1gns, chain A, domain 00	Bacillus amyloliquefaciens Water Acetone Subtilisin activity Proteolysis
1kduA00	PDB code 1kdu, chain A, domain 00	Plasminogen activation Homo sapiens Human Chemotaxis Homo
1yc6A00	PDB code 1yc6, chain A, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6B00	PDB code 1yc6, chain B, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6C00	PDB code 1yc6, chain C, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6D00	PDB code 1yc6, chain D, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6E00	PDB code 1yc6, chain E, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6F00	PDB code 1yc6, chain F, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6G00	PDB code 1yc6, chain G, domain 00	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer

Chains (1867)

ID	Title	Keywords
1yc61	PDB code 1yc6, chain 1	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1yc62	PDB code 1yc6, chain 2	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1yc63	PDB code 1yc6, chain 3	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1yc64	PDB code 1yc6, chain 4	Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer Coat protein
1gnvA	PDB code 1gnv, chain A	Bacillus amyloliquefaciens Water Subtilisin activity Proteolysis Hydrolase, serine proteinase
2k4rA	PDB code 2k4r, chain A	Prss12, nt Neurotrypsin, kringle domain, disulfide-rich protein fold, serine endopeptidase, hydrolase, extracellular proteolysis Neurotrypsin Kringle domain, nt/k, sequence database residues 84-160 Polymer
2k51A	PDB code 2k51, chain A	Prss12, nt Neurotrypsin, kringle domain, disulfide-rich protein fold, serine endopeptidase, hydrolase, extracellular proteolysis Neurotrypsin Kringle domain, nt/k, sequence database residues 84-160 Polymer
1nddB	PDB code 1ndd, chain B	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1nddA	PDB code 1ndd, chain A	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1nddC	PDB code 1ndd, chain C	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1nddD	PDB code 1ndd, chain D	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1o0eA	PDB code 1o0e, chain A	Water Monomeric Plant cysteine protease, two domain, stable at ph 2-12, hydrolase Proteolysis Ervatamin-c
1o0eB	PDB code 1o0e, chain B	Water Monomeric Plant cysteine protease, two domain, stable at ph 2-12, hydrolase Proteolysis Ervatamin-c
1yc6X	PDB code 1yc6, chain X	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6I	PDB code 1yc6, chain I	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6V	PDB code 1yc6, chain V	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6U	PDB code 1yc6, chain U	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6S	PDB code 1yc6, chain S	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6F	PDB code 1yc6, chain F	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
1yc6J	PDB code 1yc6, chain J	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer

Pdbs (930)

ID	Title	Keywords
1gnv	PDB code 1gnv	Bacillus amyloliquefaciens Water Subtilisin activity Proteolysis Hydrolase, serine proteinase
2k4r	PDB code 2k4r	Prss12, nt Neurotrypsin, kringle domain, disulfide-rich protein fold, serine endopeptidase, hydrolase, extracellular proteolysis Neurotrypsin Kringle domain, nt/k, sequence database residues 84-160 Polymer
2k51	PDB code 2k51	Prss12, nt Neurotrypsin, kringle domain, disulfide-rich protein fold, serine endopeptidase, hydrolase, extracellular proteolysis Neurotrypsin Kringle domain, nt/k, sequence database residues 84-160 Polymer
1ndd	PDB code 1ndd	Monomeric Non-polymer Water Homo sapiens Anatomical structure morphogenesis
1gns	PDB code 1gns	Bacillus amyloliquefaciens Water Acetone Subtilisin activity Proteolysis
1kdu	PDB code 1kdu	Plasminogen activation Homo sapiens Human Chemotaxis Homo
1o0e	PDB code 1o0e	Water Monomeric Plant cysteine protease, two domain, stable at ph 2-12, hydrolase Proteolysis Ervatamin-c
1yc6	PDB code 1yc6	Coat protein Water 60-meric Structural transition, proteolysis, bmv, almv, symmetry, assembly, icosahedral virus Polymer
2ntr	PDB code 2ntr	Water Homo sapiens Human (2r)-2-(5-{3-chloro-6-((2-methoxyethyl){[(1s,2s)-2-methylcyclopropyl]methyl}amino)-2-[methyl(methylsulfonyl)amino]pyridin-4-yl}-1,3,4-oxadiazol-2-yl)-1-phenylpropan-2-amine Alzheimer's disease
1ym4	PDB code 1ym4	Monomeric Water Homo sapiens Human Alzheimer's disease
2b8l	PDB code 2b8l	Water Homo sapiens Human Alzheimer's disease Protease domain (residues 43-446)
2irz	PDB code 2irz	Water Homo sapiens Human Alzheimer's disease Protease domain
2is0	PDB code 2is0	Water Homo sapiens Human (2s)-2-amino-2-benzyl-3-hydroxypropyl 3-({[(1r)-1-(4-fluorophenyl)ethyl]amino}carbonyl)-5-[methyl(methylsulfonyl)amino]benzoate Alzheimer's disease
2p83	PDB code 2p83	Monomeric Non-polymer Water Homo sapiens Human
2p8h	PDB code 2p8h	Water Homo sapiens Human Alzheimer's disease Protease domain (residues 43-446)
1u6q	PDB code 1u6q	Homo sapiens Hydrolase Human Plau Chemotaxis
1urk	PDB code 1urk	Plasminogen activation Homo sapiens Human Chemotaxis Homo
1tqf	PDB code 1tqf	Water Homo sapiens Human Alzheimer's disease Protease domain (residues 43-446)
3cib	PDB code 3cib	Non-polymer Water Homo sapiens Monomeric Human
3cic	PDB code 3cic	Non-polymer Water Homo sapiens Monomeric Human

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