CATH Domain: 1brcE02 XML data for domain: 1brcE02

Molscript image for 1brcE02
1brcE02
PDB coordinates for domain 1brcE02

PDB 1brc, Chain E, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.8
2.40.10.10.8.1
2.40.10.10.8.1.5
2.40.10.10.8.1.5.1
2.40.10.10.8.1.5.1.25

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Segment boundaries for domain 1brcE02

Chopping figure for domain 1brcE02
DomainStart PDB ResidueStop PDB Residue
1brcE01 16 27
1brcE01 121 232
1brcE02 28 120
1brcE02 233 245

Structural Neighbourhood (35 entries)

There are 35 matching structural neighberhood comparisons for CATH ID 2.40.10.10.8.1.5.1.25 (SIMAX score < 5)

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Displaying entries 1 to 35 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1hj8A02 96.80 Salmo salarTrypsin-1 precursor 2.40.10.10 103 63 100 0.56 0.56
1nn6A02 93.41 2.40.10.10 107 42 95 1.28 1.34
2qxiA02 93.26 EpitheliumEpidermis developmentEffect on morphogenesisKidneyDirectional cell growth (morphogenesis) 2.40.10.10 98 44 94 1.17 1.24
1ym0A02 93.16 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 35 91 0.87 0.95
1a7sA02 93.15 Azurophil granulePositive regulation of tumor necrosis factor biosynthetic processPositive regulation of fractalkine biosynthetic processExtracellular / secretion proteinsGlial cell migration 2.40.10.10 105 31 97 0.92 0.95
2jkhA02 92.83 Whole blood and lymphConnective tissueBlood coagulationExtracellular / secretion proteinsComplement and coagulation cascades 2.40.10.10 105 28 96 1.09 1.13
1orfA02 92.68 Protein homodimerization activityNucleusCytotoxic cell response (e.g. NK)Cleavage of laminNeuroactive ligand-receptor interaction 2.40.10.10 105 33 97 1.41 1.45
1eaxA02 92.42 Integral to plasma membraneEukaryotic plasma membrane / membrane attachedPlasma membraneSuppressor of tumorigenicity protein 14Proteolysis 2.40.10.10 115 35 88 1.33 1.50
2bz6H02 92.38 2.40.10.10 110 35 93 1.25 1.33
1bioA02 92.17 Complement factor D precursorComponent factor DComplement factor D activityHomo sapiensProteolysis 2.40.10.10 106 33 95 1.00 1.05
1gvzA02 91.90 Equus caballusKallikrein-1E2 precursor 2.40.10.10 115 34 89 1.19 1.33
3dfjA02 91.71 Prostate glandProtein processing (proteolytic)Protease, serine, 8 (prostasin)Plasma membraneExtracellular region 2.40.10.10 113 33 91 1.27 1.39
2asuB02 90.96 Homo sapiensHepatocyte growth factor-like protein precursor 2.40.10.10 103 35 90 1.37 1.52
2bvrH02 90.88 2.40.10.10 116 33 87 0.92 1.06
2anyA02 90.85 Extracellular protein degradationPlasma kallikrein precursorHomo sapiensPlasma kallikrein activityProteolysis 2.40.10.10 111 33 91 2.26 2.46
1elvA01 90.75 Whole blood and lymphComplement component 1, s subcomponentConnective tissueComplement and coagulation cascadesComplement C1s subcomponent precursor 2.40.10.10 98 27 86 1.50 1.74
2hlcA01 90.67 Hypoderma lineatumCollagenase precursor 2.40.10.10 104 28 92 2.81 3.04
3beuA02 90.46 Streptomyces griseusTrypsin precursor 2.40.10.10 99 24 91 1.80 1.97
1p57B02 90.35 Serine protease hepsinEukaryotic plasma membrane / membrane attachedIntegral to plasma membraneProtease mediated signal transductionEnzymatic activity regulation / enzyme regulator 2.40.10.10 118 32 84 1.30 1.53
2r0lA02 90.33 Serine-type endopeptidase activityHepatocyte growth factor activatorHepatocyte growth factor activator precursorProteolysisProtein binding 2.40.10.10 113 34 89 1.49 1.67
1q3xA03 90.31 2.40.10.10 100 27 90 1.59 1.76
1fiwA02 90.26 Ovis ariesAcrosin precursorDrug binding 2.40.10.10 120 35 85 1.79 2.09
2aiqA02 89.23 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 27 91 1.95 2.14
1gj7B02 88.81 Homo sapiensUrokinase-type plasminogen activator precursorProteolysisSignal transductionChemotaxis 2.40.10.10 118 28 85 1.39 1.62
1rrkA02 85.53 Complement bindingHomo sapiensComplement factor B precursorComponent factor BComplement and coagulation cascades 2.40.10.10 117 21 70 2.56 3.61
1p3cA02 84.93 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 16 89 2.40 2.67
2pkaA00 84.72 Sus scrofaGlandular kallikrein precursor 2.40.10.10 80 30 65 1.33 2.04
1agjA02 84.27 Exfoliative toxin A precursorStaphylococcus aureus 2.40.10.10 108 14 85 2.59 3.04
2o8lA02 84.13 Glutamyl endopeptidaseGlutamyl endopeptidase precursorStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 6 78 2.69 3.42
2z9iC01 80.70 Two-component system - GeneralProbable SERINE PROTEASE PEPDPutative serine protease PepDMycobacterium tuberculosis 2.40.10.10 91 9 66 2.16 3.22
1lcyA01 80.38 NucleusProtein processing (proteolytic)Serine-type endopeptidase activityApoptosis (type I programmed cell death)Endoplasmic reticulum membrane 2.40.10.10 111 13 69 2.44 3.52
1sotA01 80.27 Escherichia coli O157:H7Protease degS precursorSerine protease DegSProtein binding 2.40.10.10 118 11 69 2.66 3.83
2halA01 77.70 Human hepatitis A virus Hu/Northern Africa/MBB/1978Genome polyprotein 2.40.10.10 109 12 75 3.32 4.41
2hntC00 74.75 2.40.10.10 67 26 40 0.79 1.94
1eptA00 73.37 Sus scrofaTrypsin precursor 2.40.10.10 43 69 30 0.24 0.80
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Displaying entries 1 to 35 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1brcE02
PYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSS
PVKLNARVATNYVDWIQDTIAAN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1brcE02
PYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSS
PVKLNARVATNYVDWIQDTIAAN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:13

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"