S100 Family: 3.40.430.10.4.1.1.2

Molscript image for 1ra9A00
Representative domain: 1ra9A00
PDB coordinates for domain 1ra9A00

Classification Lineage (3.40.430.10.4.1.1.2)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.430 Dihydrofolate Reductase, subunit A
3.40.430.10 Dihydrofolate Reductase, subunit A Gene3D
3.40.430.10.4
3.40.430.10.4.1
3.40.430.10.4.1.1
3.40.430.10.4.1.1.2

Summary of Non-Redundant Representatives
- - - - - - - - 46

S100 Count Entries in S100 Family 3.40.430.10.4.1.1.2 (46)

CATH Level CATH code Domain ID Keywords Thumbnail
3.40.430.10.4.1.1.2.1 1ra9A00 dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1ra9A00
3.40.430.10.4.1.1.2.2 1ra2A00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase. Molscript image for 1ra2A00
3.40.430.10.4.1.1.2.3 1ra3A00 Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug Molscript image for 1ra3A00
3.40.430.10.4.1.1.2.4 1ra8A00 Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate Molscript image for 1ra8A00
3.40.430.10.4.1.1.2.5 1rf7A00 Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Metabolic pathways Molscript image for 1rf7A00
3.40.430.10.4.1.1.2.6 1rx2A00 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1rx2A00
3.40.430.10.4.1.1.2.7 1dyjA00 dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1dyjA00
3.40.430.10.4.1.1.2.8 1dyjB00 dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1dyjB00
3.40.430.10.4.1.1.2.9 1dyhA00 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1dyhA00
3.40.430.10.4.1.1.2.10 1dyhB00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways Molscript image for 1dyhB00
3.40.430.10.4.1.1.2.11 1dyiA00 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1dyiA00
3.40.430.10.4.1.1.2.12 1dyiB00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12 Molscript image for 1dyiB00
3.40.430.10.4.1.1.2.13 1jomA00 Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase Molscript image for 1jomA00
3.40.430.10.4.1.1.2.14 1ra1A00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12 Molscript image for 1ra1A00
3.40.430.10.4.1.1.2.15 1rc4A00 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate, Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1rc4A00
3.40.430.10.4.1.1.2.16 1rx9A00 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1rx9A00
3.40.430.10.4.1.1.2.17 3drcA00 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 3drcA00
3.40.430.10.4.1.1.2.18 3drcB00 dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process Molscript image for 3drcB00
3.40.430.10.4.1.1.2.19 1jolA00 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1jolA00
3.40.430.10.4.1.1.2.20 1jolB00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase. Molscript image for 1jolB00
3.40.430.10.4.1.1.2.21 1rg7A00 Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Metabolic pathways Molscript image for 1rg7A00
3.40.430.10.4.1.1.2.22 1rx1A00 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase, Metabolic pathways, Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1rx1A00
3.40.430.10.4.1.1.2.23 1rx6A00 Metabolic pathways, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate Molscript image for 1rx6A00
3.40.430.10.4.1.1.2.24 1rb2A00 dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1rb2A00
3.40.430.10.4.1.1.2.25 1rb2B00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase. Molscript image for 1rb2B00
3.40.430.10.4.1.1.2.26 2anqA00 Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Metabolic pathways Molscript image for 2anqA00
3.40.430.10.4.1.1.2.27 1rx3A00 Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase Molscript image for 1rx3A00
3.40.430.10.4.1.1.2.28 1rx4A00 dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Metabolic pathways, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1rx4A00
3.40.430.10.4.1.1.2.29 2inqA00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12 Molscript image for 2inqA00
3.40.430.10.4.1.1.2.30 2inqB00 dihydrofolate reductase [EC:1.5.1.3], Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Metabolic pathways, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 2inqB00
3.40.430.10.4.1.1.2.31 1drhA00 dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1drhA00
3.40.430.10.4.1.1.2.32 1rb3A00 Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12 Molscript image for 1rb3A00
3.40.430.10.4.1.1.2.33 1rb3B00 Metabolic pathways, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase Molscript image for 1rb3B00
3.40.430.10.4.1.1.2.34 1rx5A00 dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Metabolic pathways, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1rx5A00
3.40.430.10.4.1.1.2.35 1rx7A00 Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate Molscript image for 1rx7A00
3.40.430.10.4.1.1.2.36 5dfrA00 Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate Molscript image for 5dfrA00
3.40.430.10.4.1.1.2.37 1rh3A00 Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate Molscript image for 1rh3A00
3.40.430.10.4.1.1.2.38 6dfrA00 Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase Molscript image for 6dfrA00
3.40.430.10.4.1.1.2.39 7dfrA00 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase, Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 7dfrA00
3.40.430.10.4.1.1.2.40 1dreA00 dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process Molscript image for 1dreA00
3.40.430.10.4.1.1.2.41 1rd7A00 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate, Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, dihydrofolate reductase [EC:1.5.1.3] Molscript image for 1rd7A00
3.40.430.10.4.1.1.2.42 1rd7B00 Metabolic pathways, Escherichia coli K-12, Dihydrofolate reductase., Folate biosynthesis, response to drug, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, Dihydrofolate reductase, One carbon pool by folate Molscript image for 1rd7B00
3.40.430.10.4.1.1.2.43 1re7A00 Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase Molscript image for 1re7A00
3.40.430.10.4.1.1.2.44 1re7B00 One carbon pool by folate, Dihydrofolate reductase, 10-formyltetrahydrofolate biosynthetic process, dihydrofolate reductase [EC:1.5.1.3], Escherichia coli K-12, Folate biosynthesis, response to drug, Dihydrofolate reductase., Metabolic pathways Molscript image for 1re7B00
3.40.430.10.4.1.1.2.45 2anoA00 dihydrofolate reductase [EC:1.5.1.3], Metabolic pathways, Dihydrofolate reductase., Folate biosynthesis, response to drug, Escherichia coli K-12, Dihydrofolate reductase, One carbon pool by folate, 10-formyltetrahydrofolate biosynthetic process Molscript image for 2anoA00
3.40.430.10.4.1.1.2.46 1rx8A00 Metabolic pathways, Folate biosynthesis, response to drug, Dihydrofolate reductase., Escherichia coli K-12, dihydrofolate reductase [EC:1.5.1.3], 10-formyltetrahydrofolate biosynthetic process, One carbon pool by folate, Dihydrofolate reductase Molscript image for 1rx8A00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.40.430.10.4.1.1.2