S100 Family: 3.30.505.10.9.1.1.1

Molscript image for 1qadA00
Representative domain: 1qadA00
PDB coordinates for domain 1qadA00

Classification Lineage (3.30.505.10.9.1.1.1)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.505 SHC Adaptor Protein
3.30.505.10 SHC Adaptor Protein Gene3D
3.30.505.10.9
3.30.505.10.9.1
3.30.505.10.9.1.1
3.30.505.10.9.1.1.1

Summary of Non-Redundant Representatives
- - - - - - - - 3

S100 Count Entries in S100 Family 3.30.505.10.9.1.1.1 (3)

CATH Level CATH code Domain ID Keywords Thumbnail
3.30.505.10.9.1.1.1.1 1qadA00 Focal adhesion, Chagas disease, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Phosphatidylinositol signaling system, Non-small cell lung cancer, Chronic myeloid leukemia, Colorectal cancer, Toll-like receptor signaling pathway, VEGF signaling pathway, Apoptosis, Endometrial cancer, positive regulation of establishment of protein localization in plasma membrane, phosphoinositide-3-kinase, regulatory subunit, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, mTOR signaling pathway, Insulin signaling pathway, positive regulation of glucose import, Small cell lung cancer, Prostate cancer, Acute myeloid leukemia, Regulation of actin cytoskeleton, ErbB signaling pathway, Glioma, Pathways in cancer, T cell receptor signaling pathway, Pancreatic cancer, Chemokine signaling pathway, Phosphatidylinositol 3-kinase regulatory subunit alpha, Type II diabetes mellitus, Melanoma, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Bos taurus, Aldosterone-regulated sodium reabsorption Molscript image for 1qadA00
3.30.505.10.9.1.1.1.2 1bfiA00 Type II diabetes mellitus, Aldosterone-regulated sodium reabsorption, Neurotrophin signaling pathway, Leukocyte transendothelial migration, Melanoma, Bos taurus, Phosphatidylinositol 3-kinase regulatory subunit alpha, Chemokine signaling pathway, Pancreatic cancer, T cell receptor signaling pathway, Glioma, Pathways in cancer, Regulation of actin cytoskeleton, ErbB signaling pathway, Acute myeloid leukemia, Small cell lung cancer, Prostate cancer, Insulin signaling pathway, positive regulation of glucose import, mTOR signaling pathway, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, positive regulation of establishment of protein localization in plasma membrane, phosphoinositide-3-kinase, regulatory subunit, Endometrial cancer, Apoptosis, Toll-like receptor signaling pathway, VEGF signaling pathway, Non-small cell lung cancer, Phosphatidylinositol signaling system, Colorectal cancer, Chronic myeloid leukemia, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Natural killer cell mediated cytotoxicity, Fc epsilon RI signaling pathway, Chagas disease, B cell receptor signaling pathway, Focal adhesion Molscript image for 1bfiA00
3.30.505.10.9.1.1.1.3 1bfjA00 Type II diabetes mellitus, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Melanoma, Bos taurus, Aldosterone-regulated sodium reabsorption, Phosphatidylinositol 3-kinase regulatory subunit alpha, Chemokine signaling pathway, Pancreatic cancer, T cell receptor signaling pathway, ErbB signaling pathway, Regulation of actin cytoskeleton, Glioma, Pathways in cancer, Acute myeloid leukemia, Small cell lung cancer, Prostate cancer, mTOR signaling pathway, Insulin signaling pathway, positive regulation of glucose import, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, positive regulation of establishment of protein localization in plasma membrane, phosphoinositide-3-kinase, regulatory subunit, Endometrial cancer, Toll-like receptor signaling pathway, Apoptosis, VEGF signaling pathway, Phosphatidylinositol signaling system, Non-small cell lung cancer, Chronic myeloid leukemia, Colorectal cancer, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Fc epsilon RI signaling pathway, B cell receptor signaling pathway, Focal adhesion, Chagas disease Molscript image for 1bfjA00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.30.505.10.9.1.1.1