S100 Family: 3.20.20.190.7.1.1.1

Molscript image for 1djxA02
Representative domain: 1djxA02
PDB coordinates for domain 1djxA02

Classification Lineage (3.20.20.190.7.1.1.1)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.20 Alpha-Beta Barrel
3.20.20 TIM Barrel
3.20.20.190 Phosphatidylinositol (PI) phosphodiesterase Gene3D
3.20.20.190.7
3.20.20.190.7.1
3.20.20.190.7.1.1
3.20.20.190.7.1.1.1

Summary of Non-Redundant Representatives
- - - - - - - - 22

S100 Count Entries in S100 Family 3.20.20.190.7.1.1.1 (22)

CATH Level CATH code Domain ID Keywords Thumbnail
3.20.20.190.7.1.1.1.1 1djxA02 Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, cytosol, response to organic nitrogen, nucleus, response to calcium ion, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, calcium ion binding, response to aluminum ion, positive regulation of norepinephrine secretion, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, phosphoinositide phospholipase C activity, membrane fraction, membrane raft, mitochondrial membrane, response to prostaglandin F stimulus, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia Molscript image for 1djxA02
3.20.20.190.7.1.1.1.2 1djxB03 protein binding, response to peptide hormone stimulus, Inositol phosphate metabolism, mitochondrial membrane, response to prostaglandin F stimulus, Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], phosphoinositide phospholipase C activity, response to aluminum ion, positive regulation of norepinephrine secretion, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, membrane raft, membrane fraction, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus, nucleus, response to calcium ion, calcium ion binding, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, Calcium signaling pathway, cytosol, response to organic nitrogen Molscript image for 1djxB03
3.20.20.190.7.1.1.1.3 1qasA02 response to organic nitrogen, cytosol, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, Calcium signaling pathway, calcium ion binding, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus, response to calcium ion, nucleus, membrane raft, membrane fraction, phosphoinositide phospholipase C activity, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], protein binding, response to peptide hormone stimulus, Inositol phosphate metabolism, response to prostaglandin F stimulus, mitochondrial membrane Molscript image for 1qasA02
3.20.20.190.7.1.1.1.4 1qasB02 calcium ion binding, response to calcium ion, nucleus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus, cytosol, response to organic nitrogen, Calcium signaling pathway, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, Inositol phosphate metabolism, response to prostaglandin F stimulus, mitochondrial membrane, protein binding, response to peptide hormone stimulus, membrane fraction, membrane raft, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, phosphoinositide phospholipase C activity Molscript image for 1qasB02
3.20.20.190.7.1.1.1.5 1djwA02 Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, response to organic nitrogen, cytosol, response to calcium ion, nucleus, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, calcium ion binding, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, phosphoinositide phospholipase C activity, membrane fraction, membrane raft, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia Molscript image for 1djwA02
3.20.20.190.7.1.1.1.6 1djhA02 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, Calcium signaling pathway, response to organic nitrogen, cytosol, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, response to calcium ion, nucleus, calcium ion binding, phosphoinositide phospholipase C activity, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, membrane raft, membrane fraction, response to peptide hormone stimulus, protein binding, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11] Molscript image for 1djhA02
3.20.20.190.7.1.1.1.7 1djiA02 membrane raft, membrane fraction, phosphoinositide phospholipase C activity, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], response to peptide hormone stimulus, protein binding, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to organic nitrogen, cytosol, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, Calcium signaling pathway, calcium ion binding, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, response to calcium ion, nucleus Molscript image for 1djiA02
3.20.20.190.7.1.1.1.8 2isdA02 membrane fraction, membrane raft, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, phosphoinositide phospholipase C activity, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, Inositol phosphate metabolism, response to prostaglandin F stimulus, mitochondrial membrane, protein binding, response to peptide hormone stimulus, cytosol, response to organic nitrogen, Calcium signaling pathway, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, calcium ion binding, response to calcium ion, nucleus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus Molscript image for 2isdA02
3.20.20.190.7.1.1.1.9 1djwB03 response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, phosphoinositide phospholipase C activity, membrane fraction, membrane raft, response to calcium ion, nucleus, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, calcium ion binding, Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, response to organic nitrogen, cytosol Molscript image for 1djwB03
3.20.20.190.7.1.1.1.10 1djhB03 response to calcium ion, nucleus, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, calcium ion binding, Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, response to organic nitrogen, cytosol, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, phosphoinositide phospholipase C activity, membrane fraction, membrane raft Molscript image for 1djhB03
3.20.20.190.7.1.1.1.11 1djiB03 response to organic nitrogen, cytosol, Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, calcium ion binding, response to calcium ion, nucleus, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, membrane fraction, membrane raft, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, phosphoinositide phospholipase C activity, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding Molscript image for 1djiB03
3.20.20.190.7.1.1.1.12 2isdB03 response to organic nitrogen, cytosol, Calcium signaling pathway, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, calcium ion binding, response to calcium ion, nucleus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus, membrane fraction, membrane raft, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, phosphoinositide phospholipase C activity, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, Inositol phosphate metabolism, response to prostaglandin F stimulus, mitochondrial membrane, protein binding, response to peptide hormone stimulus Molscript image for 2isdB03
3.20.20.190.7.1.1.1.13 1djgA02 Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], response to peptide hormone stimulus, protein binding, mitochondrial membrane, response to prostaglandin F stimulus, Inositol phosphate metabolism, membrane raft, membrane fraction, phosphoinositide phospholipase C activity, positive regulation of norepinephrine secretion, response to aluminum ion, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, calcium ion binding, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, nucleus, response to calcium ion, cytosol, response to organic nitrogen, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, Calcium signaling pathway Molscript image for 1djgA02
3.20.20.190.7.1.1.1.14 1djgB03 calcium ion binding, response to calcium ion, nucleus, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, cytosol, response to organic nitrogen, Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, membrane fraction, membrane raft, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, phosphoinositide phospholipase C activity Molscript image for 1djgB03
3.20.20.190.7.1.1.1.15 1djyA02 nucleus, response to calcium ion, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, calcium ion binding, Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, cytosol, response to organic nitrogen, mitochondrial membrane, response to prostaglandin F stimulus, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, positive regulation of norepinephrine secretion, response to aluminum ion, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, phosphoinositide phospholipase C activity, membrane fraction, membrane raft Molscript image for 1djyA02
3.20.20.190.7.1.1.1.16 1djyB03 calcium ion binding, response to calcium ion, nucleus, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, response to organic nitrogen, cytosol, Calcium signaling pathway, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, response to peptide hormone stimulus, protein binding, membrane fraction, membrane raft, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, phosphoinositide phospholipase C activity Molscript image for 1djyB03
3.20.20.190.7.1.1.1.17 1djzA02 response to organic nitrogen, cytosol, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, Calcium signaling pathway, calcium ion binding, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, nucleus, response to calcium ion, membrane raft, membrane fraction, phosphoinositide phospholipase C activity, response to aluminum ion, positive regulation of norepinephrine secretion, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], response to peptide hormone stimulus, protein binding, mitochondrial membrane, response to prostaglandin F stimulus, Inositol phosphate metabolism Molscript image for 1djzA02
3.20.20.190.7.1.1.1.18 1qatB02 calcium ion binding, nucleus, response to calcium ion, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus, response to organic nitrogen, cytosol, Calcium signaling pathway, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phospholipase C, delta [EC:3.1.4.11], Metabolic pathways, response to hyperoxia, Inositol phosphate metabolism, mitochondrial membrane, response to prostaglandin F stimulus, protein binding, response to peptide hormone stimulus, membrane fraction, membrane raft, positive regulation of norepinephrine secretion, response to aluminum ion, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, phosphoinositide phospholipase C activity Molscript image for 1qatB02
3.20.20.190.7.1.1.1.19 1djzB03 Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], response to peptide hormone stimulus, protein binding, response to prostaglandin F stimulus, mitochondrial membrane, Inositol phosphate metabolism, membrane raft, membrane fraction, phosphoinositide phospholipase C activity, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, positive regulation of norepinephrine secretion, response to aluminum ion, calcium ion binding, Phosphatidylinositol signaling system, Rattus norvegicus, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, response to calcium ion, nucleus, response to organic nitrogen, cytosol, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, phosphatidylinositol-4,5-bisphosphate binding, Calcium signaling pathway Molscript image for 1djzB03
3.20.20.190.7.1.1.1.20 1qatA02 cytosol, response to organic nitrogen, phosphatidylinositol-4,5-bisphosphate binding, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1, Calcium signaling pathway, calcium ion binding, Phosphoinositide phospholipase C., positive regulation of inositol trisphosphate biosynthetic process, Phosphatidylinositol signaling system, Rattus norvegicus, response to calcium ion, nucleus, membrane raft, membrane fraction, phosphoinositide phospholipase C activity, elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger, response to aluminum ion, positive regulation of norepinephrine secretion, Metabolic pathways, response to hyperoxia, phospholipase C, delta [EC:3.1.4.11], protein binding, response to peptide hormone stimulus, Inositol phosphate metabolism, response to prostaglandin F stimulus, mitochondrial membrane Molscript image for 1qatA02
3.20.20.190.7.1.1.1.21 1isdA02 Molscript image for 1isdA02
3.20.20.190.7.1.1.1.22 1isdB03 Molscript image for 1isdB03

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.20.20.190.7.1.1.1