S100 Family: 2.60.40.10.56.1.1.8

Molscript image for 1svcP02
Representative domain: 1svcP02
PDB coordinates for domain 1svcP02

Classification Lineage (2.60.40.10.56.1.1.8)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.56
2.60.40.10.56.1
2.60.40.10.56.1.1
2.60.40.10.56.1.1.8

Summary of Non-Redundant Representatives
- - - - - - - - 4

S100 Count Entries in S100 Family 2.60.40.10.56.1.1.8 (4)

CATH Level CATH code Domain ID Keywords Thumbnail
2.60.40.10.56.1.1.8.1 1svcP02 RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Apoptosis, promoter binding, Adipocytokine signaling pathway, Chagas disease, B cell receptor signaling pathway, Chronic myeloid leukemia, NOD-like receptor signaling pathway, Leishmaniasis, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, inflammatory response, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, Cytosolic DNA-sensing pathway, T cell receptor signaling pathway, sequence-specific DNA binding transcription factor activity, Neurotrophin signaling pathway, transcription from RNA polymerase II promoter, Nuclear factor NF-kappa-B p105 subunit, Metabolic pathways, Prostate cancer, Small cell lung cancer, I-kappaB/NF-kappaB complex, MAPK signaling pathway, protein binding, Pathways in cancer, Epithelial cell signaling in Helicobacter pylori infection, anti-apoptosis, Acute myeloid leukemia, negative regulation of calcidiol 1-monooxygenase activity Molscript image for 1svcP02
2.60.40.10.56.1.1.8.2 1nfiB00 protein binding, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, anti-apoptosis, Acute myeloid leukemia, negative regulation of calcidiol 1-monooxygenase activity, Prostate cancer, Metabolic pathways, Small cell lung cancer, I-kappaB/NF-kappaB complex, MAPK signaling pathway, Neurotrophin signaling pathway, transcription from RNA polymerase II promoter, Nuclear factor NF-kappa-B p105 subunit, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, Cytosolic DNA-sensing pathway, sequence-specific DNA binding transcription factor activity, T cell receptor signaling pathway, Leishmaniasis, NOD-like receptor signaling pathway, Chronic myeloid leukemia, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, inflammatory response, B cell receptor signaling pathway, Chagas disease, promoter binding, Adipocytokine signaling pathway, RIG-I-like receptor signaling pathway, Apoptosis, Toll-like receptor signaling pathway Molscript image for 1nfiB00
2.60.40.10.56.1.1.8.3 1nfiD00 Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, Cytosolic DNA-sensing pathway, T cell receptor signaling pathway, sequence-specific DNA binding transcription factor activity, Neurotrophin signaling pathway, transcription from RNA polymerase II promoter, Nuclear factor NF-kappa-B p105 subunit, Metabolic pathways, Prostate cancer, Small cell lung cancer, I-kappaB/NF-kappaB complex, MAPK signaling pathway, protein binding, Pathways in cancer, Epithelial cell signaling in Helicobacter pylori infection, anti-apoptosis, Acute myeloid leukemia, negative regulation of calcidiol 1-monooxygenase activity, RIG-I-like receptor signaling pathway, Apoptosis, Toll-like receptor signaling pathway, promoter binding, Adipocytokine signaling pathway, Chagas disease, B cell receptor signaling pathway, Chronic myeloid leukemia, NOD-like receptor signaling pathway, Leishmaniasis, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, inflammatory response Molscript image for 1nfiD00
2.60.40.10.56.1.1.8.4 2o61B02 Nuclear factor NF-kappa-B p105 subunit, transcription from RNA polymerase II promoter, Neurotrophin signaling pathway, T cell receptor signaling pathway, sequence-specific DNA binding transcription factor activity, Cytosolic DNA-sensing pathway, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, Acute myeloid leukemia, negative regulation of calcidiol 1-monooxygenase activity, anti-apoptosis, Pathways in cancer, Epithelial cell signaling in Helicobacter pylori infection, protein binding, MAPK signaling pathway, Small cell lung cancer, I-kappaB/NF-kappaB complex, Metabolic pathways, Prostate cancer, Adipocytokine signaling pathway, promoter binding, Apoptosis, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, inflammatory response, NOD-like receptor signaling pathway, Leishmaniasis, Chronic myeloid leukemia, Chagas disease, B cell receptor signaling pathway Molscript image for 2o61B02

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=2.60.40.10.56.1.1.8