Homologous Superfamily: 2.40.50.40

Molscript image for 1xyiA00
Representative domain: 1xyiA00
PDB coordinates for domain 1xyiA00

Classification Lineage (2.40.50.40)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.50 OB fold (Dihydrolipoamide Acetyltransferase, E2P)
2.40.50.40 Gene3D

Summary of Non-Redundant Representatives
- - - - 25 37 61 96 301

S35 Family Entries in Homologous Superfamily 2.40.50.40 (25)

CATH Level CATH code Representative Domain Representative Keywords Representative Thumbnail Number of Domains
2.40.50.40.1 1xyiA00 Sulfolobus acidocaldariusDNA-binding protein 7d Molscript image for 1xyiA00 19
2.40.50.40.2 1c8cA00 Sulfolobus solfataricusDNA-binding protein 7d Molscript image for 1c8cA00 10
2.40.50.40.3 1b3aA00 Prion diseasesEpithelial cell signaling in Helicobacter pylori infectionChemokine signaling pathwayChagas diseaseC-C motif chemokine 5 Molscript image for 1b3aA00 26
2.40.50.40.4 1nr4C00 Chemokine activityChemokine signaling pathwayC-C motif chemokine 17ChemotaxisCell-cell signaling Molscript image for 1nr4C00 10
2.40.50.40.5 2ra4A00 Chemokine activityChemokine signaling pathwaySignal transductionExtracellular spaceC-C motif chemokine 13 Molscript image for 2ra4A00 21
2.40.50.40.6 3gv3A00 Positive regulation of monocyte chemotaxisChemokine signaling pathwayIntestinal immune network for IgA productionCell adhesionSignal transduction Molscript image for 3gv3A00 33
2.40.50.40.7 2fhtA00 Viral macrophage inflammatory protein 2Human herpesvirus 8 Molscript image for 2fhtA00 15
2.40.50.40.8 2fmmD00 SpindleChromobox protein 1Chromosome, centromeric regionChromatin bindingEnzyme binding Molscript image for 2fmmD00 18
2.40.50.40.9 2q8rE00 Signal transducer activityC-C motif chemokine 14Positive regulation of cell proliferationHomo sapiensCellular calcium ion homeostasis Molscript image for 2q8rE00 21
2.40.50.40.10 1tvxA00 Platelet basic proteinGlucose transmembrane transporter activityCytokine-cytokine receptor interactionChemokine signaling pathwayPlatelet basic protein Molscript image for 1tvxA00 47
2.40.50.40.11 2hciB00 Chemokine activitySignal transductionExtracellular spaceChemotaxisCell-cell signaling Molscript image for 2hciB00 6
2.40.50.40.12 1pfbA00 Specification of segmental identity, abdomenPRC1 complexChromobox protein 8Methylated histone residue bindingNucleolus Molscript image for 1pfbA00 16
2.40.50.40.13 1icwB00 Bladder cancerInduction of positive chemotaxisPathways in cancerEpithelial cell signaling in Helicobacter pylori infectionChemokine signaling pathway Molscript image for 1icwB00 19
2.40.50.40.14 1f2lA00 FractalkineChemokine activityDefense responseCytokine-mediated signaling pathwayCell surface Molscript image for 1f2lA00 5
2.40.50.40.15 1e0bA00 Chromatin silencing at telomereChromatin silencing at silent mating-type cassetteSister chromatid cohesionProtein bindingChromatin-associated protein swi6 Molscript image for 1e0bA00 2
2.40.50.40.16 1o7zA00 Chemokine signaling pathwayCAMP-dependent protein kinase regulator activityC-X-C motif chemokine 10Signal transductionCell-cell signaling Molscript image for 1o7zA00 13
2.40.50.40.17 1q3lA00 Chromobox protein 5Drosophila melanogasterPositive regulation of transcription, DNA-dependentChromatin bindingPolytene chromosome, telomeric region Molscript image for 1q3lA00 7
2.40.50.40.18 3d6wB01 Methyl-accepting/DNA response regulator, putativeBacillus cereus ATCC 10987 Molscript image for 3d6wB01 2
2.40.50.40.19 2nyzE00 Chemokine activityChemokine signaling pathwayLymphotactinSignal transductionC motif chemokine 1/2 Molscript image for 2nyzE00 3
2.40.50.40.20 1g6zA00 Sphingolipid biosynthetic processChromatin silencing at rDNAHistone methylationRegulation of production of siRNA involved in RNA interferenceProtein binding Molscript image for 1g6zA00 1
2.40.50.40.21 2kvmA00 Mus musculusChromobox protein homolog 7Chromobox protein 7 Molscript image for 2kvmA00 1
2.40.50.40.22 1eigA00 Chemokine activityPositive regulation of endothelial cell proliferationPositive regulation of Rac GTPase activityChemokine signaling pathwayC-C motif chemokine 24 Molscript image for 1eigA00 2
2.40.50.40.23 1rjtA00 Chemokine activityC-X-C motif chemokine 11Chemokine signaling pathwaySignal transductionChemotaxis Molscript image for 1rjtA00 1
2.40.50.40.24 1el0A00 Chemokine activityViral reproductionChemokine signaling pathwayExtracellular spaceSignal transduction Molscript image for 1el0A00 1
2.40.50.40.25 1j8iA00 Chemokine activityChemokine signaling pathwayLymphotactinSignal transductionC motif chemokine 1/2 Molscript image for 1j8iA00 2

Close Structural Clusters 2.40.50.40 (< 5Å)

Summary of "distant" structural clusters found within this level of CATH.
Cluster ID Example Domain Domains in Cluster Structural Alignment (Core) Structural Alignment (Expanded)
00002.00040.00050.00040/SSG5/1 1b3aA00 11
00002.00040.00050.00040/SSG5/2 1c8cA00 3
00002.00040.00050.00040/SSG5/3 1el0A00 2
00002.00040.00050.00040/SSG5/4 1pfbA00 4


Distant Structural Clusters 2.40.50.40 (< 9Å)

Summary of "distant" structural clusters found within this level of CATH.
Cluster ID Example Domain Domains in Cluster Structural Alignment (Core) Structural Alignment (Expanded)
00002.00040.00050.00040/SSGA9/1 1e0bA00 3
00002.00040.00050.00040/SSGA9/2 1eigA00 4


Structural Comparisons for Non-redundant S35 Representatives of 2.40.50.40 ( entries)