S100 Family: 1.20.5.170.5.1.1.2

Molscript image for 1a02J00
Representative domain: 1a02J00
PDB coordinates for domain 1a02J00

Classification Lineage (1.20.5.170.5.1.1.2)

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.5
1.20.5.170.5.1
1.20.5.170.5.1.1
1.20.5.170.5.1.1.2

Summary of Non-Redundant Representatives

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S100 Count Entries in S100 Family 1.20.5.170.5.1.1.2 (2)

CATH Level CATH code Domain ID Keywords Thumbnail
1.20.5.170.5.1.1.2.1 1a02J00 sequence-specific enhancer binding RNA polymerase II transcription factor activity, Renal cell carcinoma, SMAD protein signal transduction, promoter binding, GnRH signaling pathway, Toll-like receptor signaling pathway, negative regulation of DNA binding, Leishmaniasis, Colorectal cancer, Focal adhesion, B cell receptor signaling pathway, Chagas disease, transcription repressor activity, positive regulation by host of viral transcription, Wnt signaling pathway, Neurotrophin signaling pathway, transcription factor AP-1, T cell receptor signaling pathway, transforming growth factor beta receptor signaling pathway, Homo sapiens, R-SMAD binding, Rho GTPase activator activity, ErbB signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, SMAD protein import into nucleus, transcription coactivator activity, Transcription factor AP-1, MAPK signaling pathway, positive regulation of transcription from RNA polymerase II promoter Molscript image for 1a02J00
1.20.5.170.5.1.1.2.2 1t2kC00 Focal adhesion, B cell receptor signaling pathway, Chagas disease, negative regulation of DNA binding, Colorectal cancer, Leishmaniasis, GnRH signaling pathway, Toll-like receptor signaling pathway, sequence-specific enhancer binding RNA polymerase II transcription factor activity, Renal cell carcinoma, promoter binding, SMAD protein signal transduction, MAPK signaling pathway, Transcription factor AP-1, positive regulation of transcription from RNA polymerase II promoter, Rho GTPase activator activity, R-SMAD binding, Pathways in cancer, ErbB signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, transcription coactivator activity, SMAD protein import into nucleus, T cell receptor signaling pathway, transforming growth factor beta receptor signaling pathway, transcription factor AP-1, Homo sapiens, transcription repressor activity, Wnt signaling pathway, positive regulation by host of viral transcription, Neurotrophin signaling pathway Molscript image for 1t2kC00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: